The primary thrust of Sybil Shainwald's practice has been, and continues to be, women's health law. Ms. Shainwald pioneered Diethylstilbestrol (DES) litigation. She was co-counsel in the nation's first "DES daughter" case, Bichler v. Lilly. Since that time, she has represented thousands of women and men, from around the country and worldwide, who were exposed to DES. She has been given numerous awards for her work, including an award by the DES Cancer Network.

Throughout her years of practice, Ms. Shainwald has litigated cases involving drugs and medical devices that have inflicted harm on women and their offspring. She was a member of the national Plaintiff's Negotiating Committee for the court-appointed Plaintiff's Steering Committee in the silicone breast implant litigation. She was also named as the Chair for the Foreign Plaintiff's Subcommittee representing all the interests of foreign women.

Not only has Ms. Shainwald been an avid litigator of women's health issues, but she has been active in numerous women's health organizations as well. She has also appeared on every major TV network, written, testified and lectured extensively on obstetrical malpractice, IUDs, unnecessary hysterectomies, hormone therapy, and products liability litigation.